Stimulated whole saliva components in children with Down syndrome.
Identifieur interne : 000480 ( Main/Exploration ); précédent : 000479; suivant : 000481Stimulated whole saliva components in children with Down syndrome.
Auteurs : Walter Luiz Júnior Siqueira [Brésil] ; José NicolauSource :
- Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry [ 0275-1879 ]
Descripteurs français
- KwdFr :
- Acide N-acétyl-neuraminique (analyse), Amylases (analyse), Concentration en ions d'hydrogène (MeSH), Débit sécrétoire (MeSH), Enfant (MeSH), Femelle (MeSH), Humains (MeSH), Myeloperoxidase (analyse), Mâle (MeSH), Protéines et peptides salivaires (analyse), Salive (composition chimique), Salive (enzymologie), Salive (métabolisme), Spectrophotométrie (MeSH), Syndrome de Down (métabolisme), Études cas-témoins (MeSH).
- MESH :
- analyse : Acide N-acétyl-neuraminique, Amylases, Myeloperoxidase, Protéines et peptides salivaires.
- composition chimique : Salive.
- enzymologie : Salive.
- métabolisme : Salive, Syndrome de Down.
- Concentration en ions d'hydrogène, Débit sécrétoire, Enfant, Femelle, Humains, Mâle, Spectrophotométrie, Études cas-témoins.
English descriptors
- KwdEn :
- Amylases (analysis), Case-Control Studies (MeSH), Child (MeSH), Down Syndrome (metabolism), Female (MeSH), Humans (MeSH), Hydrogen-Ion Concentration (MeSH), Male (MeSH), N-Acetylneuraminic Acid (analysis), Peroxidase (analysis), Saliva (chemistry), Saliva (enzymology), Saliva (metabolism), Salivary Proteins and Peptides (analysis), Secretory Rate (MeSH), Spectrophotometry (MeSH).
- MESH :
- chemical , analysis : Amylases, N-Acetylneuraminic Acid, Peroxidase, Salivary Proteins and Peptides.
- chemistry : Saliva.
- enzymology : Saliva.
- metabolism : Down Syndrome, Saliva.
- Case-Control Studies, Child, Female, Humans, Hydrogen-Ion Concentration, Male, Secretory Rate, Spectrophotometry.
Abstract
The authors report on the components of stimulated whole saliva from children with Down syndrome--including pH, flow rate, sialic acid and protein concentrations, and amylase and peroxidase activity. Saliva samples were collected from 35 children aged 6-10 years. Of the participants, 17 had Down syndrome and 18 did not. To stimulate saliva production, the children chewed a piece of parafilm for 10 minutes before the sample was collected. Soon after collecting the saliva sample, the authors measured pH using a portable pH-meter. Sialic acid levels were determined with a thiobarbituric acid assay. Protein content was determined with Folin's phenol reagent. Amylase was assayed and the authors measured the maltose produced by the breakdown of starch and peroxidase using orthodianisidine. No statistically significant difference was observed in levels of sialic acid (free and total) between the two groups. Protein concentration was about 36% higher in the group with Down syndrome. However, the salivary flow rate, pH, and amylase and peroxidase activities were lower among the children with Down syndrome.
DOI: 10.1111/j.1754-4505.2002.tb00276.x
PubMed: 12790231
Affiliations:
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uniqKey="Siqueira W" first="Walter Luiz Júnior" last="Siqueira">Walter Luiz Júnior Siqueira</name><affiliation wicri:level="4"><nlm:affiliation>Oral Biology Research Center, Faculty of Dentistry, University of São Paulo, Ave. Prof. Lineu Prestes, 2227, 05508-900 São Paulo, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Oral Biology Research Center, Faculty of Dentistry, University of São Paulo, Ave. Prof. Lineu Prestes, 2227, 05508-900 São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName><orgName type="university">Université de São Paulo</orgName><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation></author><author><name sortKey="Nicolau, Jose" sort="Nicolau, Jose" uniqKey="Nicolau J" first="José" last="Nicolau">José Nicolau</name></author></analytic><series><title level="j">Special 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(analyse)</term><term>Amylases (analyse)</term><term>Concentration en ions d'hydrogène (MeSH)</term><term>Débit sécrétoire (MeSH)</term><term>Enfant (MeSH)</term><term>Femelle (MeSH)</term><term>Humains (MeSH)</term><term>Myeloperoxidase (analyse)</term><term>Mâle (MeSH)</term><term>Protéines et peptides salivaires (analyse)</term><term>Salive (composition chimique)</term><term>Salive (enzymologie)</term><term>Salive (métabolisme)</term><term>Spectrophotométrie (MeSH)</term><term>Syndrome de Down (métabolisme)</term><term>Études cas-témoins (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Amylases</term><term>N-Acetylneuraminic Acid</term><term>Peroxidase</term><term>Salivary Proteins and Peptides</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Acide N-acétyl-neuraminique</term><term>Amylases</term><term>Myeloperoxidase</term><term>Protéines et peptides salivaires</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Saliva</term></keywords><keywords scheme="MESH" qualifier="composition chimique" xml:lang="fr"><term>Salive</term></keywords><keywords scheme="MESH" qualifier="enzymologie" xml:lang="fr"><term>Salive</term></keywords><keywords scheme="MESH" qualifier="enzymology" xml:lang="en"><term>Saliva</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Down Syndrome</term><term>Saliva</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Salive</term><term>Syndrome de Down</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Case-Control Studies</term><term>Child</term><term>Female</term><term>Humans</term><term>Hydrogen-Ion Concentration</term><term>Male</term><term>Secretory Rate</term><term>Spectrophotometry</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Concentration en ions d'hydrogène</term><term>Débit sécrétoire</term><term>Enfant</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Spectrophotométrie</term><term>Études cas-témoins</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The authors report on the components of stimulated whole saliva from children with Down syndrome--including pH, flow rate, sialic acid and protein concentrations, and amylase and peroxidase activity. Saliva samples were collected from 35 children aged 6-10 years. Of the participants, 17 had Down syndrome and 18 did not. To stimulate saliva production, the children chewed a piece of parafilm for 10 minutes before the sample was collected. Soon after collecting the saliva sample, the authors measured pH using a portable pH-meter. Sialic acid levels were determined with a thiobarbituric acid assay. Protein content was determined with Folin's phenol reagent. Amylase was assayed and the authors measured the maltose produced by the breakdown of starch and peroxidase using orthodianisidine. No statistically significant difference was observed in levels of sialic acid (free and total) between the two groups. Protein concentration was about 36% higher in the group with Down syndrome. However, the salivary flow rate, pH, and amylase and peroxidase activities were lower among the children with Down syndrome.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">12790231</PMID><DateCompleted><Year>2003</Year><Month>06</Month><Day>18</Day></DateCompleted><DateRevised><Year>2019</Year><Month>10</Month><Day>25</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0275-1879</ISSN><JournalIssue CitedMedium="Print"><Volume>22</Volume><Issue>6</Issue><PubDate><MedlineDate>2002 Nov-Dec</MedlineDate></PubDate></JournalIssue><Title>Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry</Title><ISOAbbreviation>Spec Care Dentist</ISOAbbreviation></Journal><ArticleTitle>Stimulated whole saliva components in children with Down syndrome.</ArticleTitle><Pagination><MedlinePgn>226-30</MedlinePgn></Pagination><Abstract><AbstractText>The authors report on the components of stimulated whole saliva from children with Down syndrome--including pH, flow rate, sialic acid and protein concentrations, and amylase and peroxidase activity. Saliva samples were collected from 35 children aged 6-10 years. Of the participants, 17 had Down syndrome and 18 did not. To stimulate saliva production, the children chewed a piece of parafilm for 10 minutes before the sample was collected. Soon after collecting the saliva sample, the authors measured pH using a portable pH-meter. Sialic acid levels were determined with a thiobarbituric acid assay. Protein content was determined with Folin's phenol reagent. Amylase was assayed and the authors measured the maltose produced by the breakdown of starch and peroxidase using orthodianisidine. No statistically significant difference was observed in levels of sialic acid (free and total) between the two groups. Protein concentration was about 36% higher in the group with Down syndrome. However, the salivary flow rate, pH, and amylase and peroxidase activities were lower among the children with Down syndrome.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Siqueira</LastName><ForeName>Walter Luiz Júnior</ForeName><Initials>WL</Initials><AffiliationInfo><Affiliation>Oral Biology Research Center, Faculty of Dentistry, University of São Paulo, Ave. Prof. Lineu Prestes, 2227, 05508-900 São Paulo, Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nicolau</LastName><ForeName>José</ForeName><Initials>J</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Spec Care Dentist</MedlineTA><NlmUniqueID>8103755</NlmUniqueID><ISSNLinking>0275-1879</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D012471">Salivary Proteins and Peptides</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 1.11.1.7</RegistryNumber><NameOfSubstance UI="D009195">Peroxidase</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 3.2.1.-</RegistryNumber><NameOfSubstance UI="D000681">Amylases</NameOfSubstance></Chemical><Chemical><RegistryNumber>GZP2782OP0</RegistryNumber><NameOfSubstance UI="D019158">N-Acetylneuraminic Acid</NameOfSubstance></Chemical></ChemicalList><CitationSubset>D</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000681" MajorTopicYN="N">Amylases</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016022" MajorTopicYN="N">Case-Control Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004314" MajorTopicYN="N">Down Syndrome</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006863" MajorTopicYN="N">Hydrogen-Ion Concentration</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D019158" MajorTopicYN="N">N-Acetylneuraminic Acid</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009195" MajorTopicYN="N">Peroxidase</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012463" MajorTopicYN="N">Saliva</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName><QualifierName UI="Q000201" MajorTopicYN="N">enzymology</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012471" MajorTopicYN="N">Salivary Proteins and Peptides</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012636" MajorTopicYN="N">Secretory Rate</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013053" MajorTopicYN="N">Spectrophotometry</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2003</Year><Month>6</Month><Day>7</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2003</Year><Month>6</Month><Day>19</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2003</Year><Month>6</Month><Day>7</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">12790231</ArticleId><ArticleId IdType="doi">10.1111/j.1754-4505.2002.tb00276.x</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Brésil</li></country><region><li>État de São Paulo</li></region><settlement><li>São Paulo</li></settlement><orgName><li>Université de São Paulo</li></orgName></list><tree><noCountry><name sortKey="Nicolau, Jose" sort="Nicolau, Jose" uniqKey="Nicolau J" first="José" last="Nicolau">José Nicolau</name></noCountry><country name="Brésil"><region name="État de São Paulo"><name sortKey="Siqueira, Walter Luiz Junior" sort="Siqueira, Walter Luiz Junior" uniqKey="Siqueira W" first="Walter Luiz Júnior" last="Siqueira">Walter Luiz Júnior Siqueira</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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